Microfluidic immunohistochemistry for rapid detection of diagnostic and predictive biomarkers on non-small cell lung carcinoma
Considering the increasing cancer incidence, a concomitantly accurate and time-efficient IHC is clinically highly relevant. The automated microfluidic staining device enables for a precisely controlled immune-reaction to take place in an extremely short incubation time; typically, a complete microfluidic IHC lasts less than 12 minutes on frozen tissue section.
The microfluidic IHC resulted in fast automated high-quality staining for all assessed markers on NSCLC. Subsequent clinical validation on a large cohort will provide a diagnostic tool for biomarkers detection in a turnaround time far beyond the existing automated stainers.