Immunohistochemistry (IHC) is the most widely used cancer biomarker test for tissues. This technique uses antibodies to detect antigens present at the surface of tissue sections, most often Formalin-Fixed Paraffin-Embedded (FFPE) samples. Thanks to an enzyme-antibody conjugate that reacts with a soluble substrate, the colored product deposits on the tissue surface and can be visualized under a bright-field microscope.
The number of biomarkers being discovered is constantly increasing. The need for faster IHC turnaround times in histopathology laboratories is growing as this method is used for diagnosing many different types of cancer.
Lunaphore’s microfluidic technology FFeX is able to dramatically reduce FFPE IHC turnaround times to an average of 20-30 minutes and has the potential of becoming the new gold standard in automated stainers. For research laboratories, an open device based on FFeX, LabSat® Research, is available.
Lunaphore is currently developing a high-throughput instrument for research laboratories with high-plex requirements*.